Aqueous Carbon Quantum Dots
Product Description
Alfa Chemistry can provide customers with aqueous carbon quantum dots at 405-565 nm. Compared to traditional fluorescent organic dyes and semiconductor quantum dots, aqueous carbon quantum dots are chemically stable, inert, form stable colloidal solutions, and are highly resistance to photobleaching. Therefore, the fluorescence properties of aqueous carbon quantum dots are widely used in sensing, biomedical imaging, catalysis, and energy research.
Applications
Anti-cancer
Prasad et al. reported the synthesis of CQDs by carbonizing the organic molecule, 1,7'-dimethyl-2'-propyl-1H,3'H-[2,5']biphenylimidazole (DPBI). XRD results confirmed the crystallinity of the DPBI-based CQDs, where a peak of 25.8° was observed attributed to the reflective surface (002). In addition, the results of HRTEM studies show that the morphology of the particles is spherical, with an average size between 2 and 3 nm and a planar spacing of 0.329 nm between two lattice stripes. The biological activity of the prepared CQDs was tested for their intrinsic antitumor properties, and CQDs showed significant anticancer properties against breast cancer cell lines in vitro and specificity of action against tumor cells in chicken gallbladder membranes (CAM) in vitro. This was used as an in vivo model to study the different effects of CQDs, where they showed minimal cytotoxicity against normal cells, which is consistent with in vitro studies analyzing the activity of CQDs against red blood cells (RBCs) and white blood cells (WBCs).
Fig. 1 HRTEM image of DPBI-based CQDs showing interplanar distance between two lattice fringes. (Prasad et al., 2019)
Luminescent Displays
To go beyond the PC60 surfactant structure, the bilayer micelle morphology in water has prompted the exploration of changing protocols to produce new morphologies. Furthermore, the low photoluminescence quantum yield of water-based fullerene particles encourages high fluorescence to create a luminescent display. With this in mind, Yu et al. built new hybrid n-type nanospheres with carbon quantum dot (CQD)-embedded PC60-PC61BM particles, treated with two different protocols. The homogenizer-assisted PC60-CQD-PC61BM produced a watermelon-shaped spherical particle, while a circular morphology with randomly embedded CQD was observed in the microwave-treated hybrid. More surprisingly, the watermelon-shaped colloid induced efficient fluorescence resonance energy transfer (FRET) between the C60 molecules of CQD and PC61BM, and the FRET-mediated emission feature gradually diminished with the collapse of the stripe pattern. This phenomenon led to the appearance of different fluorescent colors in the colloidal printed films.
Fig.2 TEM images of homogenizer-assisted PC60-CQD-PC61BM particles depending on the PC60 concentration and their corresponding suggested structures (first column). (Yu et al., 2019)
Alfa Chemistry can provide a variety of complex and customized fluorescent quantum dot products. Our products involve perovskites precursors, perovskites quantum dots, quantum dot kit, single layer quantum dots, upconverting nanoparticles and other fluorescent quantum dots. Alfa Chemistry provides products with high fluorescence quantum yield, stable quality and relatively low price. Our products are constantly updated. If the product you need is not in our catalog, please feel free to contact us, we provide relevant custom services.
References
- Prasad, K. S. , G. Shruthi , and C. Shivamallu . One-pot synthesis of aqueous carbon quantum dots using bibenzoimidazolyl derivative and their antitumor activity against breast cancer cell lines[J]. Inorganic Chemistry Communications, 2019, 101:11-15.
- Yu, J. K. , P. Guo , and R. D. Schaller . Aqueous Carbon Quantum Dots-embedded PC60-PC61BM Nanospheres for Ecological Fluorescent Printing: Contrasting FRET Signals Between Watermelon-like and Random Morphologies[J]. Journal of Physical Chemistry Letters, 2019, 2019(XXXX).
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