Product Description
Alfa Chemistry can provide cadmium telluride (CdTe) quantum dot powders in the spectral emission range from 510 nm to 780 nm wavelengths. They are charged inorganic particles that can be used as powders or dispersions. CdTe quantum dots are nanoparticles and, like some semiconductor crystals, have the novel property of having an extremely narrow emission spectrum (Gaussian distribution) proportional to the particle size. The smaller the particle, the more blueshift it emits, and conversely, the larger the particle size, the more redshift it emits, thus allowing a full spectral spectrum to be emitted from the same material. CdTe quantum dots can transform light emitting diodes (LEDs) from mere display devices to lighting devices that create the first solid-state light source. Cadmium telluride (CdTe) quantum dot powders also readily form colloidal solutions in water. Available in powder form and readily soluble in water. It is ideal as a marker.
Luminous peak width: 30-100 nm (depending on emission wavelength)
Stokes shift to first exciton: 10-20 nm
Typical quantum yield: 15-90 % (depending on emission wavelength)
Applications
Fluorescence Detection
Yang et al. used CdTe quantum dots to detect glutamate dehydrogenase (GLDH), a mitochondrial enzyme present in cells of all tissues, with the highest GLDH activity in the mitochondria of liver cells. Therefore, GLDH levels are measured clinically as an indicator molecule for the diagnosis of hepatocyte damage. The NAD+/GLDH system combines the unique optical properties of quantum dots with the specificity and high efficiency of the enzyme to achieve a simple and rapid detection of GLDH, which is an important indicator molecule of liver injury and has important applications in the diagnosis of different liver diseases. This assay can be used for the determination of a wide range of GLDH concentrations (10 ~ 1000 U/L) and has potential clinical applications.
Fig.1 Schematic illustration for the assay of golutamate dehydrogenase ( GLDH) activity. (Yang et al, 2014)
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References
- Yang M. , et al. A Turn-on Fluorescent Probe Based on Quantum Dots for Detection of Trace Glutamate Dehydrogenase. Chinese Journal of Analytical Chemistry, 2014,42(03):436-440.
- Wu P. , Yan L. and Yan X. P. CdTe Quantum Dots (QDs) Based Kinetic Discrimination of Fe2+ and Fe3+, and CdTe QDs-Fenton Hybrid System for Sensitive Photoluminescent Detection of Fe2+. Analytical Chemistry, 2009, 81(15).
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