Product Description
Carbon quantum dots, a new class of carbon nanomaterials with sizes below 10 nm, are a type of spherical carbon particles. Compared with metal quantum dots, carbon quantum dots are almost non-toxic and pose little environmental hazard. Since the discovery of CQDs, they have gradually replaced traditional semiconductor quantum dots as a new star for bioimaging and cell labeling because of their small particle size, low toxicity, good water solubility, and adjustable fluorescence.
Applications
Biomedical Applications
The unparalleled properties of carbon quantum dots and their inexpensive production contribute to their use in biomedical applications, especially as antibacterial and anti-biocontamination coatings. Fluorescent hydrophobic carbon quantum dots were synthesized by a bottom-up condensation method and used to deposit homogeneous Langmuir-Blodgett films on different substrates. It was found that such quantum dots produce singly linear oxygen upon blue light irradiation. Antibacterial and anti-biofouling tests on four different bacterial strains (Escherichia coli, Staphylococcus aureus, Bacillus cereus and Pseudomonas aeruginosa) showed enhanced antibacterial and anti-biofouling activity of the hydrophobic carbon dot films under blue light irradiation. In addition, hydrophobic quantum dots showed no cytotoxic effect on mouse fibroblast cell lines. These properties make hydrophobic carbon quantum dot films potentially useful as excellent antibacterial and anti-biofouling coatings for different biomedical applications.
Fig.1 Antibacterial and fouling properties of Langmuir-Blodgett films by carbon quantum dots. (Stankovic, 2018)
Metal Ions Detection
In 2018, Guo et al. prepared high fluorescent nitrogen and phosphorus co-doped carbon quantum dots (NP-CQDs) by heat treatment of the mixture of citric acid and ophosphoethanolamine, which have good stability and photostability, and the quantum yield was about 8.45%. NP-CQDs can be used for sensitive selective fluorescence detection of Fe3+ ions. In 2018 Zhang et al. reported a method for preparing nitrogen-doped lignin carbon quantum dots (N-L-CQDs) using alkaline lignin carbon source and deep eutectic solvent (DES) as solution and nitrogen source to detect Fe3+ ions. The results showed that the fluorescence probe had good sensitivity and selectivity for Fe3+ ions, and the detection limit is 0.44 μm (Fig. 2).
Fig. 2 Schematic diagram of N-L-CQDs synthesis and detection mechanism. (Guo, 2018)
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References
- Stankovic, N., et al. Antibacterial and Antibiofouling Properties of Light Triggered Fluorescent Hydrophobic Carbon Quantum Dots Langmuir-Blodgett Thin Films. Acs Sustainable Chemistry & Engineering (2018):acssuschemeng.7b04566.
- Guo, et al. Solid phase synthesis of nitrogen and phosphor co-doped carbon quantum dots for sensing Fe3+ and the enhanced photocatalytic degradation of dyes. Sensors and Actuators, B. Chemical, 2018.
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