PbS-PEG-NH2 Quantum Dots
Product Description
Alfa Chemistry can provide customers with PbS-PEG-NH2 quantum dot products, whose surface is covered by hydrophilic group PEG-NH2, and should be stored out of direct sunlight and in a sealed dark place at 4 degrees. We can provide our customers with quantum dots in different grams from 920 nm to 1120 nm. The product has the characteristics of uniform particle size, broad absorption spectrum, narrow and symmetrical emission spectrum, high and stable fluorescence intensity, etc. It can be used in electronic communication, liquid crystal display, light-emitting diode, solar cell, bio-fluorescent labeling and other fields.
Applications
Nanomedicine
Quantum dots (QDs) are potentially beneficial semiconductor nanocrystals used for diagnostic and therapeutic purposes. However, the chemical composition of quantum dots has raised concerns about their potential toxicity. While thorough examination using specific biochemical endpoints is necessary to assess the toxicity of QDs, understanding the interactions of QDs, particularly their uptake and intracellular fate, is also essential to determine their potentially dangerous effects. Clift et al. investigated a series of surface-coated QDs (and amino(NH2)polyethylene glycol (PEG)) in J774.A1 "murine macrophages" in terms of uptake and intracellular fate. Furthermore, elemental transmission electron microscopy confirmed that NH2(PEG)QDs were located in the membrane-bound region at this time point. The data from this study combined with current knowledge suggest that the intracellular localization of QDs may be directly related to their toxicity.
Fig.1 Image of a J774.A1 murine "macrophage-like" cell, as observed via TEM. The macrophage cell was exposed to NH2 (PEG) QDs for 2 h at 40 nM. In images A–C COOH QDs are shown to be present within membrane bound vesicles. (Clift et al., 2011)
Alfa Chemistry can provide a variety of complex and customized fluorescent quantum dot products. Our products involve perovskites precursors, perovskites quantum dots, quantum dot kit, single layer quantum dots, upconverting nanoparticles and other fluorescent quantum dots. Alfa Chemistry provides products with high fluorescence quantum yield, stable quality and relatively low price. Our products are constantly updated. If the product you need is not in our catalog, please feel free to contact us, we provide relevant custom services.
Reference
- Clift, Mjd , et al. The uptake and intracellular fate of a series of different surface coated quantum dots in vitro[J]. Toxicology, 2011, 286(1-3):58-68.
* It should be noted that our service is only used for research, not for clinical use.
